Lamean^® – Sodium Hyaluronate 1.2%

Because of its lubricating and viscoelastic properties, transparency, and ability to protect corneal endothelial cells, Lamean^®/ Lamean^® Plus helps maintain anterior chamber depth and visibility, minimizes interaction between tissues, and acts as a tamponade and vitreous substitute during retinal reattachment surgery. Lamean^®/ Lamean^® Plus also preserves tissue integrity and good visibility when used to fill the anterior and posterior segments of the eye following open sky procedures.

Lamean^® contains 12 mg/mL and Lamean^® Plus contains 16 mg/mL of sodium hyaluronate dissolved in a physiological sodium chloride phosphate buffer solution.

Lamean^®/ Lamean^® Plus is indicated for use as a surgical aid in ophthalmic anterior and posterior segment procedures including:

• Extraction of a cataract
• Implantation of an intraocular lens (IOL)
• Corneal transplantation surgery
• Glaucoma filtering surgery
• Surgical procedures to reattach the retina

Lamean^®/ Lamean^® Plus is injected into the eye by a specialist doctor using a sterile cannula during eye surgeries.

Each package of Lamean^®/Lamean^® Plus contains one sterile prefilled syringe of 0.8 ml, one sterile disposable cannula, and a leaflet.

Lamean^®/ Lamean^® Plus has an average molecular weight greater than 1,000,000 Daltons, is non-antigenic, non-pyrogenic, does not cause foreign body reactions, and is well tolerated in the eye. It does not interfere with the normal wound healing process.

Lamean^®/ Lamean^® Plus should be stored in a refrigerator at 2-8°C, and protected from freezing or extreme heat. This product should be placed at room temperature for about 20 minutes before use.

• After surgery, a temporary increase in intraocular pressure may occur, which may be due to the presence of previous glaucoma in the eye or the surgery itself.
• The product should be removed from the anterior chamber of the eye at the end of the surgery to prevent an increase in intraocular pressure after the operation.
• If the sterile packaging is open or damaged, the product should not be used.
• The unused contents of the syringe should be discarded after a single use.
• The cannula should not be reused.